王杰，研究员，博导，兰州大学与耶鲁大学联合培养博士，耶鲁大学博士后中科院青年创新促进会会员，湖北省杰青，湖北省科协“荆楚科普大讲堂”报告团成员。现任Neuroscience bulletin青年编委（IF:5.2），中国神经科学学会麻醉与脑功能分会—青年副主任委员，中国图学学会医学图像与设备专业委员会—常委，中国药物滥用防治协会-成瘾与脑科学分会—委员，湖北省医学生物免疫学会第二届理事。主持国家自然科学基金（3项），湖北省重点项目，武汉市高价值专利培育等9项。参与科技部863计划、基金委重点项目等4项。

　　主要从事整合小动物磁共振成像与病毒示踪技术开发新型基因编码生物磁共振成像技术，并将其用于胶质细胞和神经元的在体成像研究；系统整合光/药理遗传学、电生理和膜片钳等技术对其相关功能进行验证。目前，在PNAS，Journal of Clinical Investigations（高被引论文），Molecular Psychiatry，JCI insight（封面文章），Neuroimage（2）等SCI期刊以第一/通讯作者发表SCI论文44篇（近3年26篇，中科院1区7篇，2区14篇），申请国家发明专利16项（已授权4项），软件著作权9项。

2019，国家自然科学基金面上项目，项目批准号：31970973 ；项目名称：建立多模态活体长时程同步解析脑结构与功能网络的新技术和新方法，起止年月：2020/01-2023/12，58万元，主持 

2017，国家自然科学基金面上项目，项目批准号： 31771193；项目名称：基于脑网络研究脑内长期乙醛蓄积诱发脑损伤的多层次表征，起止年月：2018/01-2021/12，55万元，主持 

2012，国家自然科学基金青年项目1项，项目批准号：21105116；项目名称：小鼠大脑中能量代谢和神经传递动力学参数的NMR定量测定方法及应用；起止年月：2012/01-2014/12， 25万元，已结题，主持。 

2017, 物数所基金，青年交叉学科研究项目，项目名称：新型降压药物研发及其疗效的多模态磁共振成像评估，起止年月：2018-2019，15万元，主持。 

2017,2018 中国科学院人事局，项目名称：第三届全国神经环路示踪技术培训班，起止年月：2018年，2019年，15万元，主持。 

2014，国家高技术研究发展计划（863计划），项目批准号：2015AA020508；项目名称：活体脑多光子显微结构与功能成像关键技术研究，2015/01-2017/12，32万元/465万元，参加，物数所负责人 

2014，湖北省自然科学基金面上项目，项目批准号：2015CFB296；项目名称：酒精成瘾对大鼠大脑代谢通路的改变及其作用机制的研究，2015/01-2016/12，6万元，已结题，主持； 

2012，国家自然科学基金，项目批准号：91132306；项目名称：光遗传技术在情感和记忆神经回路调控研究中的应用，2012-01至2015-12，350万元，已结题，项目骨干 

2016，国家自然科学基金国际（地区）合作与交流项目，批准号：81661148053；项目名称：气味相关的两个大脑半球之间的联系；2016/10-2019/09，175万元，在研，项目骨干； 

2012，神经回路结构研究新技术新方法及其应用，战略先导计划，课题组承担988万，结题中，项目骨干

第一作者论文

 

1. J. Wang, H.Y. Du, L.H. Jiang, X.X. Ma, R.A. de Graaf, K.L. Behar, G.F. Mason, Oxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure, P Natl Acad Sci USA, 110 (2013) 14444-14449.

 

2. J. Wang, H.Y. Du, X.X. Ma, B. Pittman, L. Castracane, T.K. Li, K.L. Behar, G.F. Mason, Metabolic products of [2-C-13]ethanol in the rat brain after chronic ethanol exposure, J Neurochem, 127 (2013) 353-364.

 

3. J. Wang, L.H. Jiang, H.Y. Du, K.L. Behar, T.K. Li, G.F. Mason, Ethanol as Metabolic Precursor and Fuel for the Brain, Alcohol Clin Exp Res, 37 (2013) 254a-254a.  Alcoholism-Clinical and Experimental Research

 

4. J. Wang, P.C. Nicholas, D. Kim, L.H. Jiang, L. Castracane, J.M. Macdonald, F.T. Crews, G.F. Mason, Metabolic Products of [1-13c] Ethanol in the Awake Rat Brain, Alcohol Clin Exp Res, 36 (2012) 83a-83a.

 

5. J. Wang, L.H. Jiang, H.Y. Du, G.F. Mason, An Ethanol Vapor Chamber for Small Animals, Alcohol Clin Exp Res, 36 (2012) 29a-29a.

 

6. J. Wang, L.H. Jiang, H.Y. Du, G.F. Mason, An ethanol vapor chamber system for small animals, J Neurosci Meth, 208 (2012) 79-85.

 

7. J. Wang, L.H. Jiang, Y.F. Jiang, X.X. Ma, G.M.I. Chowdhury, G.F. Mason, Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine, J Neurochem, 113 (2010) 1447-1458.

 

8. J. Wang, H.X. Liu, S. Qin, X.J. Yao, M.C. Liu, Z.D. Hu, B.T. Fan, Study on the structure-activity relationship of new anti-HIV nucleoside derivatives based on the support vector machine method, Qsar Comb Sci, 26 (2007) 161-172.

 

9. J. Wang, H. Du, X. Yao, Z. Hu, Using classification structure pharmacokinetic relationship (SCPR) method to predict drug bioavailability based on grid-search support vector machine, Anal Chim Acta, 601 (2007) 156-163.

 

10.  J. Wang, H. Du, H. Liu, X. Yao, Z. Hu, B. Fan, Prediction of surface tension for common compounds based on novel methods using heuristic method and support vector machine, Talanta, 73 (2007) 147-156.

 

11.  J. Wang, H.X. Liu, H.Z. Si, X.J. Yao, M.C. Liu, Z.D. Hu, Prediction of the power rotation of the amino acid based on the quantitative structure-property relationship method, Chinese J Anal Chem, 34 (2006) 1759-1762.

 

 

 

通讯作者论文

 

33. Mei Li#, Zhuang Liu#, Yang   Wu, Ning Zheng, Xiaodong Liu, Aoling Cai, Danhao Zheng, Jinpiao Zhu, Jinfeng   Wu, Lingling Xu, Xihai Li, Ling-Qiang Zhu, Anne Manyande, Fuqiang Xu*,   Jie Wang*, In vivo Imaging   of Astrocytes in the Whole Brain with Engineered AAVs and Diffusion Weighted   Magnetic Resonance Imaging, Molecular   Psychiatry, Accepted (中科院1区；JCR1区；IF=15.992，封面文章)

 

32. Yuanyuan   Fang#, Chang Chen#, Qi Zhong, Lirong Wang, Zhu Gui, Jinpiao Zhu, Anne   Manyande, Fuqiang Xu, Jie Wang*,   Zongze Zhang*, Cerebral Glucose Metabolism Is Affected by Chronic   Pain-Mediated Cognitive Impairment in Adolescent Rats, Molecular Neurobiology, Accepted, (中科院2区；JCR1区；IF=5.59)

 

31. Tian Tian#,   Jinfeng Wu#, Tao Chen, Jia Li, Su Yan, Yiran Zhou, Xiaolong Peng, Yuanhao Li,   Ning Zheng, Aoling Cai, Qin Ning, Hongbing Xiang, Fuqiang Xu, Yuanyuan Qin*,   Wenzhen Zhu*, Jie Wang*, Long-term   follow-up studies for dynamic brain changes in recovered COVID-19 patients   without neurological manifestations. JCI insight,  2022;7(4):e155827 (中科院1区；JCR1区；IF=8.315，封面文章)

 

30. Yuanyuan   Qin#; Jinfeng Wu#; Tao Chen#; Jia Li; Guiling Zhang; Di Wu; Yiran Zhou; Ning   Zheng; Aoling Cai; Qin Ning; Anne Manyande; Fuqiang Xu; Jie Wang*; Wenzhen Zhu*; Long-term micro-structure and cerebral   blood flow changes in patients recovered from COVID-19 without neurological   manifestations, Journal of Clinical Investigation, 2021, 131(8):e147329 . (中科院1区；JCR1区；IF=14.808，高被引论文，获国际同行专家述评)

 

 

29. Ning Zheng（郑宁）#; Mei Li（李梅）#; Yang Wu; Challika Kaewborisuth; Zhen Li; Zhu Gui; Jinfeng Wu; Aoling Cai; Kangguang Lin; Kuan-Pin Su; Hongbing Xiang; Xuebi Tian; Anne Manyande, Fuqiang Xu; Jie Wang（王杰）*; A novel technology for in vivo detection of cell type-specific 1 neural connection with AQP1-encoding rAAV2-retro vector and metal-free MRI, Neuroimage, 258 (2022) 119402.（中科院1区；JCR1区；IF=6.556）

 

28. Meimei Guo（郭美美硕士）#; Yuxiang Wu（吴钰祥）#; Danhao Zheng; Lei Chen; Bingrui Xiong; Jinfeng Wu; Ke Li; Li Wang; Kangguang Lin; Zongze Zhang; Anne Manyande; Fuqiang Xu; Jie Wang（王杰）*; Mian Peng（彭勉）*,  Preoperative acute sleep deprivation causes postoperative pain hypersensitivity and abnormal cerebral function, Neuroscience Bulletin, Accepted. （中科院2区；JCR2区；IF=5.203） ——合作单位：武汉大学中南医院彭勉教授，联培学生郭美美

 

27. Zhen Li(李珍)，Tianning Sun，Zhigang He，Zhixiao Li，Wencui Zhang，Jie Wang（王杰），Hongbing Xiang（项红兵），SCFAs ameliorate chronic postsurgical pain-related cognition dysfunction via the ACSS2-HAD in rats，Molecular neurobiology（Accepted）——合作单位：华中科技大学同济医院项红兵教授，联培学生李珍

 

26. Dandan Sun#; Huiling Guo#; Fay Y. Womer;   Jingyu Yang; Jingwei Tang; Juan Liu; Yue Zhu; Jia Duan; Zhengwu Peng; Huaning   Wang; Qingrong Tan; Qiwen Zhu; Yange Wei; Yanbo Zhang; Yanqing Tang; Xizhe   Zhang*; Fuqiang Xu*; Jie Wang*; Fei Wang*, Frontal-posterior   functional imbalance and aberrant function developmental patterns in   schizophrenia. Transl Psychiat 11(1), (2021), 495. (中科院1区；JCR1区；IF=6.222)

 

25. Meng-Yuan   Chen#; Zhu Gui#; Ke-Ke Chen;   Jiang-Hui Ding; Jin-Gang He; Jun Xiong; Jia-Le Li; Jie Wang*; Bi-Feng Yuan*;   Yu-Qi Feng, Adolescent alcohol exposure alters DNA and RNA modifications in   peripheral blood by liquid chromatography-tandem mass spectrometry analysis; Chinese   Chemical Letters, 2021, Accepted.  (中科院2区；JCR1区；IF=6.779)

 

24. Ying Liu,   Shuang Li, Bo Rao, Ning Zheng, Jie   Wang*, Linlin Bi*, Haibo Xu*, Distinct hypothalamic paraventricular   nucleus inputs to the cingulate cortex and paraventricular thalamic nucleus   modulate anxiety and arousal. Frontiers in Pharmacology, (2022)   13: 814623 (中科院2区；JCR1区；IF=5.811).

 

23.  Lei Chen#;   Shuang Li#; Ying Zhou; Taotao Liu; Aoling Cai; Zongze Zhang; Fuqiang Xu; Ane   Manyande; Jie Wang*; Mian Peng*; Neuronal mechanisms of adenosine A2A   receptors in the loss of consciousness induced by propofol general anesthesia   with functional magnetic resonance imaging, Journal of Neurochemistry,   2021, 156(6): 1020-1032.  (中科院2区；JCR1区；IF=5.372)

 

22. Aoling Cai#; Ning Zheng#; Garth J. Thompson; Yang Wu;   Binbin Nie; Kunzhang Lin; Peng Su; Jinfeng Wu; Anne Manyande; Ling-Qiang Zhu;   Jie Wang*; Fuqiang Xu*; Longitudinal neural connection detection using   a Ferritin-encoding Adeno-associated virus vector and in vivo MRI   method, Human Brain   Mapping, 2021, 42: 5010–5022..  (中科院2区；JCR1区；IF=5.038)

 

21. Hongying Du,   Jin Zhang, Siqi Wang, Anne Manyande, Jie   Wang*, Effect of high-intensity ultrasonic treatment on the   physicochemical, structural, rheological, behavioral, and foaming properties   of pumpkin (Cucurbita moschata Duch.)-seed protein isolates. LWT,   155 (2022) 112952  (中科院1区；JCR1区；IF=4.952)

 

20. Meimei Guo; Yuanyuan Fang; Jinpiao Zhu; Chang Chen;   Zongze Zhang; Xuebi Tian; Hongbing Xiang; Anne Manyande; Mojtaba Ehsanifar;   Ahmad Jonidi Jafari; Fuqiang Xu; Jie Wang*; Mian Peng*; Investigation   of metabolic kinetics in different brain regions of awake rats using the [1H-13C]-NMR technique, Journal of Pharmaceutical and   Biomedical Analysis, 2021, 204: 114240.  (中科院2区；JCR2区；IF=3.935)

 

19. Danhao   Zheng#; Zhao Li#; Shuang Li; Xihai Li; Ghulam Mustafa Kamal; Chaoyang Liu;   Anne Manyande; Fuqiang Xu; Qingjia Bao*; Jie   Wang*; Identification of metabolic kinetic patterns in different brain   regions using metabolomics methods coupled with various discriminant   approaches, Journal of Pharmaceutical and Biomedical Analysis, 2021, 198:   114027.  (中科院2区；JCR2区；IF=3.935)

 

18. Yue Liu#; Binbin Nie#; Taotao Liu; Ning   Zheng; Zeyuan Liu; Baoci Shan; Lihong Jiang; Anne Manyande; Xihai Li; Fuqiang   Xu*; Jie Wang*; Variations of   Brain Functional Connectivity in Alcohol-Preferring and Non-Preferring Rats   with Consecutive Alcohol Training or Acute Alcohol Administration, Brain   Sci. 2021, 11, 1474.  (中科院3区；JCR3区；IF=3.394)

 

17. Yue Liu#;   Shusheng Yang#; Erli Cai#; Li Lin; Peng Zeng; Binbin Nie; Fuqiang Xu; Qing   Tian*; Jie Wang*; Functions of   lactate in the brain of rat with intracerebral hemorrhage evaluated with   MRI/MRS and in vitro approaches, CNS Neuroscience & Therapeutics,   2020 26: 1031-1044.  (中科院2区；JCR1区；IF=5.243

 

16. Xiaoping   Rao; Jie Wang*, Neuronal Network   Dissection with Neurotropic Virus Tracing. Neurosci. Bull. 2020,   36, (3), 199-201.  (中科院2区；JCR2区；IF=5.203)

 

15. Taotao Liu;   Zhengqian Li; Jindan He; Ning Yang; Dengyang Han; Yue Li; Xuebi Tian; Huili   Liu; Anne Manyande; Hongbing Xiang; Fuqiang Xu; Jie Wang*; Xiangyang Guo*, Regional Metabolic Patterns of   Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by   H-1-NMR Dynamic Mapping Method. Neurosci. Bull. 2020, 36, (1),   25-38.  (中科院2区；JCR2区；IF=5.203

 

14. Liang Wu#;   Zhanfeng Niu#; Xulei Hu; Huili Liu; Shuang Li; Lei Chen; Danhao Zheng; Zhuang   Liu; Taotao Liu; Fuqiang Xu; Anne Manyande; Jie Wang*; Hechun Xia*; Regional cerebral metabolic levels and   turnover of the awake rats after acute or chronic spinal cord injury. FASEB   Journal, 2020, 34: 10547-10559.  (中科院2区；JCR1区；IF=5.192

 

13. Wenchang   Zhou#; Aoling Cai#; Binbin Nie#; Wen Zhang; Ting Yang; Ning Zheng; Anne   Manyande; Xuxia Wang; Fuqiang Xu; Xuebi Tian*; Jie Wang*; Investigation of robust visual reaction and functional   connectivity in the rat brain induced by rocuronium bromide with functional   MRI, American Journal of Translational Research, 2020, 12:   2396-2408.  (中科院3区；JCR2区；IF=4.06)

 

12. T. Hu; Q. F.   Zhu; Y. N. Hu; G. M. Kamal; Y. Q. Feng; A. Manyande; J. Wang*; F. Q. Xu*; Qualitative and Quantitative Analysis of   Regional Cerebral Free Fatty Acids in Rats Using the Stable Isotope Labeling   Liquid Chromatography-Mass Spectrometry Method, Molecules, 2020, 25.  (中科院3区；JCR2区；IF=4.412)

 

11. Jingyu Yang,   Huiling Guo, Dandan Sun, Jia Duan, Xiaoping Rao, Fuqiang Xu, Anne Manyande, Jie Wang*, Fei Wang*,  Brain metabolite alterations in a   schizophrenia rat model evaluated by proton nuclear magnetic resonance   approaches, American Journal of Translational Research, 2019;11(9):5919-5931.    (中科院3区；JCR2区；IF=4.06)

 

10. Cheng Huang1,   JieWang1, NingWang, Feng Du,Wei Xiong, Junchao Qian, Kai Zhong,   Aoling Cai, Shijin Xu, Jun Huang, Xueying Cheng, Shufang He, Ye Zhang, Effect   of myocardial ischemic preconditioning on ischemia-reperfusion   stimulation-induced activation in rat thoracic spinal cord with functional   MRI, International Journal   of Cardiology   285 (2019) 59–64.  (中科院2区；JCR2区；IF=4.164)

 

9. Hongying Du1,*,y,   Shuang Li1, Yingfeng Zhang, Huiling Guo, Liang Wu, Huili Liu, Anne   Manyande, Fuqiang Xu, and Jie Wang*,   NMR Based Metabolomics Comparison of Dierent Blood Sampling Techniques in   Awake and Anesthetized Rats, Molecules 2019, 24, 2542  (中科院3区；JCR2区；IF=4.412)

 

8. N. Zheng1,   P. Su1, Y. Liu, H. Wang, B. Nie, X. Fang, Y. Xu, K. Lin, P. Lv, X.   He, Y. Guo, B. Shan, A. Manyande, J.   Wang*, F. Xu*, Detection of neural connections with ex vivo MRI using a   ferritin-encoding trans-synaptic virus, NeuroImage, 197 (2019) 133-142  (中科院1区；JCR1区；IF=6.556)

 

7.  Jie Wang1, *, Hao-Long   Zeng1, Hongying Du, Zeyuan Liu, Ji Cheng, Taotao Liu, Ting Hu, Ghulam   Mustafa Kamal, Xihai Li, Huili Liu, Fuqiang Xu, Evaluation of metabolites   extraction strategies for identifying different brain regions and their relationship   with alcohol preference and gender difference using NMR metabolomics, Talanta,   2018, 179:369-376.  (中科院2   区；JCR1区；IF=6.057)

 

6. H.L. Zeng1,   Q. Yang1, H.Y. Du, H.J Li, Y. Shen, T.T. Liu, X. Chen, G.M. Kamal,   Q. Guan, L.M. Cheng, J. Wang*, F.Q. Xu*, Proteomics and metabolomics analysis   of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring   rats, Oncotarget, 2017, 8(60)102020-102032.  (中科院未收录；JCR1区；IF=5.168)

 

5. T.T.   Liu, Z.G. He, X.B. Tian, G.M. Kamal, Z.X. Li, Z.Y. Liu, H.L. Liu, F.Q. Xu, J. Wang*, H.B. Xiang*,   Specific patterns of spinal metabolites underlying alpha-Me-5-HT-evoked   pruritus compared with histamine and capsaicin assessed by proton nuclear   magnetic resonance spectroscopy, BBA-Mol Basis Dis, 1863 (2017)   1222-1230.  (中科院2区；JCR1区；IF=5.187)

 

4. Y.   Liu, J. Cheng, H.L. Liu, Y.H. Deng, J. Wang*, F.Q. Xu*,   NMRSpec:   An integrated software package for processing and analyzing one dimensional   nuclear magnetic resonance spectra, Chemometr Intell Lab, 162 (2017) 142-148.  (中科院3区；JCR1区；IF=3.491)

 

3. R.X.   Chen, Y.H. Deng, L. Yang, J. Wang*, F.Q. Xu*,   Determination of Histamine by High-Performance Liquid Chromatography After   Precolumn Derivatization with o-Phthalaldehyde-Sulfite, Journal of Chromatographic Science, 54 (2016) 547-553.  (中科院4区；JCR4区；IF=1.618)

 

2. R.X.   Chen, L. Wang, J. Wang*, F.Q. Xu*,   Determination of Whiteners in Cosmetics by Microdialysis and High-Performance   Liquid Chromatography, Analytical Letters, 48 (2015)   2159-2171.  (中科院4区；JCR3区；IF=2.329)

 

1:  R.X. Chen, Y.H. Deng, J. Yao, G.M. Kamal, J. Wang*, F.Q. Xu*, Assessment of Amino Acid Neurotransmitters in Rat Brain Microdialysis Samples by High-Performance Liquid Chromatography with Coulometric Detection, Journal of Liquid Chromatography & Related Technologies, 38 (2015) 1439-1447.  (中科院4区；JCR4区；IF=1.312)

奖学金

2006年度 兰州大学优秀共产党员 兰州大学化学化工学院优秀共产党员 香港求是奖学金、凯莱英奖学金、海正奖学金 

2004年度 优秀生源专项奖学金 

2000-2004年度 多次荣获国家奖学金，兰州大学校一等，二等、三等奖学金，海正奖学金，优秀共产党员以及社会实践先进个人等荣誉称号。 

个人荣誉 

2018年度和2019年度 中国科学院优秀党务工作者 

2016年度 中国科学院武汉分院优秀共产党员，中国科学院武汉物理与数学研究所优秀共产党员 

2014年度 中国科学院武汉物理与数学研究所优秀共产党员 科研奖励 2019年度 湖北省科技进步二等奖 

2016年度 第17届磁共振在生物系统应用国际会议（日本东京）国际青年科学家奖 

2006年度 兰州市科学技术进步奖二等奖 2005年度 甘肃省科学技术进步奖三等奖， 

2003-2004年度 甘肃省优秀新产品、新技术